Gilbert's syndrome - causes, symptoms and treatment methods

Gilbert's syndrome is a harmless condition but often causes fear of the disease diagnosed. It is probably the most common medical syndrome identified.Gilbert 's syndrome from a slightly elevated level of bilirubin is detected in the blood, without other liver function abnormalities and no evidence of liver disease. It 's the most common hereditary cause of increased bilirubin, and is found in up to 5% of the population. unconjugated hyperbilirubinemia is Gilbert's syndrome inUntil the system of conjugation of bilirubin uridine diphosphate glucuronyl intraday enzyme have been recognized. The main symptom is otherwise harmless jaundice which does not require treatment, caused by an increase of conjugated bilirubin in the blood. Also known as constitutional hepatic dysfunction, unconjugated benign bilirubinemia and familial nonhemolytic jaundice, Gilbert's syndrome usually do not require treatment or complications.bilirubin levels are rising especially in Gilbert's syndrome with starvation and dehydration.

Gilbert's syndrome is usually recognized in the second or third decade of life and is rarely diagnosed before puberty. Men are often affected than women. You can also coexist with the common conditions with unconjugated hyperbilirubinemia, such as thalassemia and glucose-6-phosphate associated. Gilbert is often diagnosed in late teens and early twenties. TheDisease is inherited and is relatively common affecting about 1 in 20. The source of this hyperbilirubinemia is the activity of the enzyme (glucuronyl) reduced using bilirubin and some other lipophilic molecules. In people with Gilbert's syndrome, the bilirubin level often goes up and down. Sometimes it can be within the normal range. People with Gilbert's syndrome is an inherited abnormality that causes reduced production of an enzyme involvedTreatment of bilirubin. It is often diagnosed only in the late teens or twenties.

Causes of Gilbert's syndrome

The most common causes and risk factors of Gilbert's syndrome are:

Mutation of UDP-glucuronosyltransferase.

Fasting: The result is an increase of conjugated bilirubin in plasma.

Stress, such as trauma and overexertion.

Menstruation.

Occurring diseases, such as a viral infection.

SymptomsGilbert's syndrome

Some sign and symptoms associated with Gilbert's syndrome are:

Gilbert's syndrome is usually harmless and causes no symptoms, although some complain about excessive fatigue affected.

Mild jaundice (yellowing of the skin and whites of the eyes).

Loss of appetite.

Abdominal pain from time to time ().

Weakness.

Treatment of Gilbert's syndrome

Here is a list of methods for the treatment of GilbertSyndrome:

Gilbert's syndrome appears to be a learning disorder, but usually does not need medical attention.

The drugs that the enzyme may work better if used to treat jaundice can be a problem.

Phenobarbital in small doses can sometimes help clear the jaundice.

People with Gilbert's syndrome usually do not need long-term monitoring of their condition or repeated blood tests.

If you are suffering from jaundice, the barbituratePhenobarbital may reduce bilirubin levels.

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